Neural precursor cells (NSCs), a type of stem cell is treatment of diseases such as spinal traumatic injury, amyotrophic lateral sclerosis and multiple sclerosis. Team of physicians at UOF San diego school of medicine injects NCSs in rat and concluded,
“This injection technique allows the delivery of high cell numbers from a single injection,” said Marsala. “Cells with proliferative properties, such as glial progenitors, then migrate into the spinal parenchyma and populate over time in multiple spinal segments as well as the brain stem. Injected cells acquire the functional properties consistent with surrounding host cells.”
Further research to be carried on animals that mimics anatomy and size of human. “The goal is to define the optimal cell dosing and timing of cell delivery after spinal injury, which is associated with the best treatment effect,” said Marsala.
A micrograph shows effective migration of subpially injected human oligodendrocytes (a type of support cell in the central nervous system, colored here in green) into the spinal cord gray matter (left) and into the cerebellum (right) of an immunodeficient rat. Red indicates signal for oligodendrocyte marker; blue is signal for neuronal marker.
Source: https://stemcellsjournals.onlinelibrary.wiley.com/doi/10.1002/sctm.19-0156



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